Early brain changes in people whose dream‑enacting sleep began or worsened after SSRI antidepressants

Who could benefit from this research

What this research studies

If your dream‑enacting behaviors began or got worse after starting an SSRI, the research team will study you to look for early signs of neurodegeneration. You may be asked to complete sleep recordings, tests of thinking and movement, color vision checks, and possibly brain imaging or other biomarker tests. The investigators will compare people with SSRI‑unmasked RBD to other RBD patients and to control participants to see whether the SSRI group already shows subtle cognitive, visual, or motor changes. Learning these patterns could help doctors spot who is at higher risk of developing Lewy body dementia or Parkinsonian disorders years before clear dementia appears.

Why it matters

Where this research is happening

• University of Minnesota
  Minneapolis, United States Active

Researchers

• Principal investigator: Howell, Michael J — University of Minnesota
• Study coordinator: Howell, Michael J

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.