E-Fusion: a bedside aid for titrating vasopressors to keep blood pressure steady
Official title: A Feasibility Study for a Clinical Decision Support System to Assist with Vasopressor Titration
Funded at Autonomous Healthcare, INC. · NIH-11406875 · Data updated 2026-11-12
A bedside device helps clinicians adjust vasopressor doses to keep a patient’s blood pressure stable during surgery or in the ICU.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Autonomous Healthcare, INC. NIH-funded |
| Lab location | 1 site (Santa Clara, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $305,999 |
| NIH project number | 1R43HL187059-01 |
| Project ID | NIH-11406875 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults undergoing surgery or in critical care who require vasopressor support to manage blood pressure.
✕Less likely to help
Patients not receiving vasopressor therapy or not at risk of intraoperative/ICU hypotension may not benefit.
What this research studies
This project tests a bedside device that watches a patient’s mean arterial pressure (MAP) and its changes to suggest how to adjust vasopressor infusions. It aims to reduce clinician workload and minimize periods of low blood pressure in high-risk patients. The study focuses on real-time MAP monitoring and guided dosing to help anesthesiologists and critical care nurses keep MAP near the target. The approach is designed for use in operating rooms and intensive care units where blood pressure management is critical. If successful, it could simplify a complex, high-stakes task and improve patient stability.
Why it matters
Potential benefit: If successful, the device could make blood pressure management safer and easier for patients undergoing surgery or in the ICU.
How similar studies have gone: Earlier work suggests that algorithmic support can reduce clinician workload and improve target-achievement, but this feasibility study will test the device in a real clinical setting.
Where this research is happening
-
Autonomous Healthcare, INC.
Santa Clara, United States Active
Researchers
- Principal investigator: Gholami, Behnood — Autonomous Healthcare, INC.
- Study coordinator: Gholami, Behnood
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.