Drug-resistant germs in nursing homes

Epidemiology of MDRO Carriage in Nursing Homes

['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-11332674

This project looks at how common dangerous drug-resistant infections are and how they affect people who live in nursing homes.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA-IRVINE (nih funded)
Locations1 site (IRVINE, UNITED STATES)
Trial IDNIH-11332674 on ClinicalTrials.gov

What this research studies

If you live in a nursing home, this project will test residents for five major drug-resistant organisms (MRSA, VRE, ESBL-producing bacteria, CRE, and Candida auris) to see who is carrying them. The team will collect swabs and link those results to health records to track who develops infections or other problems over time. Researchers will map how these germs move within and between nursing homes and study factors like shared spaces, staff movement, and infection-prevention practices that may drive spread. The information will be used to design practical steps nursing homes can take to lower infections and protect residents.

Who could benefit from this research

Good fit: Ideal participants are people living in nursing homes, especially those with long stays, medical devices (for example catheters), frequent hospital transfers, or complex medical needs.

Not a fit: People who do not live in or interact with nursing homes or healthcare settings are unlikely to see direct benefits from this project.

Why it matters

Potential benefit: If successful, this work could lead to better screening and prevention steps that reduce dangerous drug-resistant infections in nursing homes.

How similar studies have performed: Hospital-based programs have reduced MDRO spread with targeted surveillance and infection-control measures, but applying multi-pathogen surveillance and prevention specifically in nursing homes is newer and less proven.

Where this research is happening

IRVINE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Disease, Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.