Down syndrome biospecimen bank
The INCLUDE Project Down Syndrome Biorepository (DS-Biorepository)
This project builds a shared biobank of blood, tissue, and health data to support research on health issues affecting people with Down syndrome.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11199005 on NIH RePORTER |
What this research studies
If I or my family join, the project will collect and store biological samples and linked health information from people with Down syndrome, such as blood, tissue, and medical records. They will bring together samples and data from existing Down syndrome groups (Human Trisome Project, ABC-DS, and the Down Syndrome Biobank Consortium) and harmonize how specimens are collected and stored so researchers can use them securely. The biorepository aims to include people of different ages, races, and backgrounds and to connect samples to genetic, clinical, and social information. Qualified researchers will be able to request specimens and data to study conditions like Alzheimer’s disease, immune problems, heart defects, and autism, which could speed discovery.
Who could benefit from this research
Good fit: Ideal candidates are people with Down syndrome (and sometimes family members) who are willing to donate biological samples and share medical records or study data.
Not a fit: People without Down syndrome, or those unwilling or unable to provide samples or share health information, would not directly benefit from participation.
Why it matters
Potential benefit: If successful, the biobank could speed up discoveries about biological markers and treatments for conditions that affect people with Down syndrome by making high-quality samples and data widely available.
How similar studies have performed: Existing Down syndrome cohorts and biobanks (like HTP and ABC-DS) have supported important findings, so this effort builds on proven resources.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Espinosa, Joaquin M. — University of Colorado Denver
- Study coordinator: Espinosa, Joaquin M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.