Diverse human genome reference collection
Center for Human Genome Reference Diversity
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA SANTA CRUZ · NIH-11196746
Building a richer set of complete human genomes from people of many ancestries so researchers can better understand genetic differences across populations.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA SANTA CRUZ (nih funded) |
| Locations | 1 site (SANTA CRUZ, UNITED STATES) |
| Trial ID | NIH-11196746 on ClinicalTrials.gov |
What this research studies
Volunteers who agree to open sharing will be asked to provide a biological sample that can also be turned into a cell line for future research. Scientists will use advanced sequencing methods to produce complete, telomere-to-telomere genome assemblies for about 200 additional people. New software and assembly methods will be refined to make these high-quality genomes accurate and cost-effective. All data, protocols, and tools will be shared openly and an ethics team will guide consent and privacy practices.
Who could benefit from this research
Good fit: Ideal participants are people from diverse or underrepresented ancestral backgrounds who are willing to provide a biological sample and consent to open-access use of their genomic data.
Not a fit: People who do not want their genetic information shared openly or who expect immediate medical treatment from participating are unlikely to receive direct benefit.
Why it matters
Potential benefit: If successful, this work could make genetic tests and research more accurate and more equitable for people from underrepresented ancestries.
How similar studies have performed: Earlier phases of the Human Pangenome Project and other reference genome efforts have produced high-quality assemblies, and this project builds on that demonstrated progress.
Where this research is happening
SANTA CRUZ, UNITED STATES
- UNIVERSITY OF CALIFORNIA SANTA CRUZ — SANTA CRUZ, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MIGA, KAREN HAYDEN — UNIVERSITY OF CALIFORNIA SANTA CRUZ
- Study coordinator: MIGA, KAREN HAYDEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.