Discovering ways to slow down aging

Interventions That Retard Mammalian Aging

NIH-funded research Jackson Laboratory · NIH-11101394

This program tests different medicines to see if they can help mice live longer, hoping to find new ways to slow aging in people.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionJackson Laboratory NIH-funded
Lab location1 site (Bar Harbor, United States)
Project IDNIH-11101394 on NIH RePORTER

What this research studies

This program looks for new ways to help us live longer and healthier lives by testing various medicines. Scientists carefully give these medicines to mice and watch to see if their lifespan increases or if they stay healthier for longer. The goal is to understand how these medicines work and if they could eventually lead to treatments that slow down aging or prevent age-related diseases in humans. This work involves multiple research sites testing many different agents using standardized methods.

Who could benefit from this research

Good fit: This foundational research is not directly recruiting patients but aims to benefit adults interested in future anti-aging therapies.

Not a fit: Patients seeking immediate treatment for existing conditions would not directly benefit from this early-stage animal research.

Why it matters

Potential benefit: If successful, this research could lead to new medicines that help people live longer, healthier lives by slowing the aging process or delaying age-related illnesses.

How similar studies have performed: Several agents, including rapamycin and acarbose, have already shown statistically significant effects on longevity in mice within this program.

Where this research is happening

Bar Harbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.