Discovering new natural products from bacteria using genomics
Official title: Genomics Accelerated Natural Product Discovery
Funded at Vanderbilt University · NIH-11224349 · Data updated 2026-11-12
This study is exploring how bacteria create new substances that could lead to new medicines, and it's for anyone interested in how these discoveries might help improve treatments for various health conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project start | January 1, 2025 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $190,586 |
| NIH project number | 7R01GM123998-09 |
| Project ID | NIH-11224349 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions that may be treated by novel natural products derived from bacterial sources.
✕Less likely to help
Patients with conditions that are not addressed by natural products or those not responsive to such treatments may not benefit from this research.
What this research studies
This research focuses on identifying new molecular structures produced by bacteria through unique enzymatic processes. By utilizing advanced genomic techniques and big data, the team aims to bioinformatically classify and experimentally characterize these novel natural products. The project emphasizes the importance of bacterial natural products as they have historically led to significant medical advancements. Patients may benefit from new therapeutic compounds derived from these discoveries.
Why it matters
Potential benefit: If successful, this research could lead to the development of new drugs that improve treatment options for various diseases.
How similar studies have gone: Previous research has shown success in discovering new drugs from bacterial natural products, indicating a promising approach in this area.
Where this research is happening
-
Vanderbilt University
Nashville, United States Active
Researchers
- Principal investigator: Mitchell, Douglas Alan — Vanderbilt University
- Study coordinator: Mitchell, Douglas Alan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.