Discovering new genes and technologies for non-human primates' immune systems
Non-human primate MHC and KIR Allele Discovery and Typing Technology Development
['FUNDING_OTHER'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-10625822
This study is all about finding new genes that help understand how the immune systems of non-human primates work, which can help researchers learn more about immune responses and improve transplantation studies, and the best part is that all the findings will be shared openly with the research community!
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-10625822 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying new genes and alleles related to the immune systems of non-human primates (NHP), specifically looking at MHC Class I and II genes, Killer-cell Immunoglobulin-like Receptors (KIR), and Fc Receptors (FcR). The team will develop advanced genotyping technologies that will be freely available to the NHP research community. By utilizing whole genome and whole exome sequencing, they aim to generate comprehensive genetic data that will aid in understanding immune responses and support transplantation studies in NHP models. This work will also include making all findings publicly accessible to enhance collaboration and data sharing.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be those involved in non-human primate studies, particularly in immunology and transplantation.
Not a fit: Patients who are not involved in non-human primate research or those with conditions unrelated to immune system studies may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatments for diseases affecting non-human primates, which may also translate to better therapies for human patients.
How similar studies have performed: Other research has shown success in using similar genomic approaches to enhance understanding of immune systems in various species, indicating that this approach has potential for impactful results.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: O'CONNER, PHD, DAVID — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: O'CONNER, PHD, DAVID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.