NIH-funded research Sbir 2 grant

DiSCERN: a smart, at-home tool to pick and adjust advanced Parkinson’s therapies

Official title: DiSCERN: Advanced PD Therapy Candidacy and Evaluation System

Funded at Great Lakes Neurotechnologies · NIH-11405932 · Data updated 2026-11-12

A smart, at-home system uses a watch, phone, app, and online portal to help people with Parkinson’s identify whether they may benefit from advanced treatments and track when those treatments need adjustments.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionGreat Lakes Neurotechnologies
NIH-funded
Lab location1 site (Independence, UNITED STATES)
Project startSeptember 20, 2018
Project endApril 30, 2028
Funding year2026
Award (this year)$949,447
NIH project number2R44MD013767-04A1
Project IDNIH-11405932 on NIH RePORTER

Who could benefit from this research

Could help

Adults with Parkinson’s disease experiencing motor fluctuations who may be candidates for advanced therapies and have limited access to movement disorder specialists.

Less likely to help

Patients who are stable on current therapy with no consideration for advanced therapies or who cannot use digital health tools may see limited benefit.

What this research studies

DiSCERN aims to turn a telemedicine tool into a commercially available product that helps patients with Parkinson’s decide if and when advanced therapies are right for them. The system combines a smartwatch, a smartphone app, a web portal for clinicians, and secure cloud storage to monitor symptoms and candidacy for advanced therapies remotely. By improving access to expertise and enabling continuous, remote screening, the project seeks to reduce disparities in specialty care for patients in rural or low-resource settings while empowering patients and caregivers. The research will integrate user-friendly interfaces, data collection, and clinician workflows to support timely, personalized treatment decisions in real-world care.

Why it matters

Potential benefit: If successful, patients could gain earlier and more equitable access to appropriate advanced therapies and better symptom management.

How similar studies have gone: Prior telemedicine tools have shown promise in improving access and decision-making, but this project advances commercialization and remote screening for AT candidacy in PD.

Where this research is happening

  • Great Lakes Neurotechnologies
    Independence, United States
    Active

Researchers

  • Principal investigator: Heldman, Dustin a. — Great Lakes Neurotechnologies
  • Study coordinator: Heldman, Dustin a.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.