DISC device to translate deep brain signals into speech

DIrectional and SCalable (DISC) Microelectrode Array for Speech Decoding

NIH-funded research University of Texas Hlth Sci Ctr Houston · NIH-11055381

A novel implantable brain sensor that reads deeper speech-related signals to help people who cannot speak because of stroke, neurological injury, or paralysis.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11055381 on NIH RePORTER

What this research studies

This project is building a new implant called DISC that combines stereo-EEG depth probes with high-density microelectrodes to capture brain activity from deep speech areas. The design uses a method called "substrate shielding" to boost signal size, reduce noise, and better separate overlapping brain sources. Early in vivo results show improved signal amplitude, signal-to-noise ratio, and source separation, and the team plans to test word-decoding both offline and in real time. If you have severe speech loss or are a patient undergoing clinical depth recordings, researchers may ask to record your brain signals to try translating them into words.

Who could benefit from this research

Good fit: Ideal candidates are people with severe speech impairment (aphasia, dysarthria, or locked-in syndrome) or patients already undergoing stereo-EEG monitoring for epilepsy who can accept additional recording tests.

Not a fit: People with only mild speech issues, those who cannot undergo invasive recordings, or those whose speech problems are caused by non-neural issues (vocal cord or airway problems) are unlikely to benefit.

Why it matters

Potential benefit: Could enable devices that turn intended speech-related brain activity into audible or text output to restore communication for people with severe speech loss.

How similar studies have performed: Other brain-computer interface work has shown promise decoding speech-related signals, but this deep, directional micro/macro array approach is novel and at an early translational stage.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.