Digital wearable biomarkers to track motor function in Charcot-Marie-Tooth disease
Official title: Digital Biomarkers of Motor Function as Drug Development Tools in Charcot-Marie-Tooth Disease
Funded at Biosensics, LLC · NIH-11621286 · Data updated 2026-11-12
A study uses wearable sensors to measure real-life movement and hand function in people with Charcot-Marie-Tooth disease to support drug development.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biosensics, LLC NIH-funded |
| Lab location | 1 site (Newton, UNITED STATES) |
| Project start | September 25, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,100,000 |
| NIH project number | 1U01FD009005-01 |
| Project ID | NIH-11621286 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with Charcot-Marie-Tooth disease who can wear sensors and participate in at-home monitoring.
✕Less likely to help
Individuals who cannot participate in at-home monitoring or have conditions limiting wearable use may not benefit.
What this research studies
This project tests wearable-based digital health tools to measure how CMT affects movement and hand use in patients at home. Researchers will collect continuous data from wearables to capture motor function over time and relate it to disease status. The goal is to provide more sensitive, real-world measures that could help evaluate potential treatments for CMT. Participants will wear sensors, complete simple tasks, and share data with the research team across the study period.
Why it matters
Potential benefit: If successful, patients could see more accurate monitoring of disease progression and quicker assessment of new treatments.
How similar studies have gone: Previous work showed feasibility and initial clinical validity of wearables for at-home motor assessment in CMT.
Where this research is happening
-
Biosensics, LLC
Newton, United States Active
Researchers
- Principal investigator: Vaziri, Ashkan — Biosensics, LLC
- Study coordinator: Vaziri, Ashkan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.