Digital memory app to help people with Down syndrome remember personal events

Use of a digital memory prosthetic to support autobiographical memory in down syndrome

NIH-funded research Boston College · NIH-11169719

This project uses a smartphone app called HippoCamera to help people with Down syndrome remember specific events from their lives.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionBoston College NIH-funded
Lab location1 site (Chestnut Hill, United States)
Project IDNIH-11169719 on NIH RePORTER

What this research studies

You would use a smartphone app called HippoCamera to record brief video or audio memories from your day and replay them later. The app uses a research-based algorithm to curate and optimize those replays to strengthen memory consolidation. Study staff will collect memory tests and other measures to see if regular use improves detailed autobiographical recall and related mood or independence. The work is led by researchers at Boston College and runs through mid-2026.

Who could benefit from this research

Good fit: Ideal candidates are people with Down syndrome who have difficulty recalling specific personal events and who can use a smartphone themselves or with caregiver help.

Not a fit: People without Down syndrome or those who cannot use a smartphone or have very severe cognitive, sensory, or motor impairments that prevent participation are unlikely to benefit from this project.

Why it matters

Potential benefit: If successful, the app could help people with Down syndrome remember personal events more clearly, which may support greater independence and lower anxiety or depression.

How similar studies have performed: Related memory-support apps and replay-based approaches have shown promise in other groups, but applying HippoCamera specifically to people with Down syndrome is a new direction.

Where this research is happening

Chestnut Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.