Digital health tool to monitor and manage CAR-T recovery symptoms
Official title: Improving patient outcomes through a digital health delivered intervention to monitor and manage symptoms after chimeric antigen receptor T-cell therapy
Funded at Mcc Health, INC · NIH-11405310 · Data updated 2026-11-12
A patient-facing digital program helps people who had CAR-T therapy track and manage common recovery symptoms to feel better and stay on top of their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mcc Health, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $201,112 |
| NIH project number | 1R41CA314618-01 |
| Project ID | NIH-11405310 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults treated with CAR-T therapy for hematological diseases who are discharged and navigating early recovery (up to 90 days).
✕Less likely to help
Patients not using digital tools or without access to digital devices may not experience direct benefits.
What this research studies
This project will develop a user-friendly digital intervention (MCC-CAR-T) that patients use after CAR-T therapy to monitor symptoms, receive guidance, and build confidence in managing their recovery. It will test feasibility, acceptability, and impact on self-efficacy and quality of life during the first 90 days after discharge. The team will tailor symptom monitoring to common CAR-T–related issues like fatigue, pain, infections, and neurotoxic effects, with feedback to patients and caregivers. If successful, the program could become a practical tool to reduce symptom burden and potentially lower readmission risk. The study is conducted in people treated for hematologic diseases who are navigating outpatient recovery after CAR-T treatment.
Why it matters
Potential benefit: If the digital tool proves feasible and acceptable, patients could experience better symptom control, higher self-efficacy, and improved quality of life during CAR-T recovery.
How similar studies have gone: Previous symptom-monitoring interventions in other populations showed reduced symptom burden and improved QoL, but this is the first focused on CAR-T recovery.
Where this research is happening
-
Mcc Health, INC
New York, United States Active
Researchers
- Principal investigator: Landau, Daniella — Mcc Health, INC
- Study coordinator: Landau, Daniella
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.