Differences in blood vessel properties in the brain
Brain Vascular Heterogeneity
['FUNDING_R21'] · JOHNS HOPKINS UNIVERSITY · NIH-10437595
This study looks at how blood vessels in different parts of the brain work in conditions like stroke and multiple sclerosis, aiming to understand how these differences affect brain health and recovery, especially by focusing on the role of special support cells.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10437595 on ClinicalTrials.gov |
What this research studies
This research investigates how blood vessels in different areas of the brain, particularly gray and white matter, behave differently in various neurological conditions such as stroke and multiple sclerosis. Using advanced imaging techniques and cellular analysis, the study aims to understand the unique characteristics of these blood vessels, including their molecular composition and response to injury or disease. By examining the role of supporting cells like astrocytes and pericytes, the research seeks to uncover how these differences contribute to brain health and disease outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with neurological conditions such as stroke, multiple sclerosis, or cerebral malaria.
Not a fit: Patients with purely non-vascular neurological disorders or those without any neurological symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for neurological conditions by targeting the specific vascular abnormalities identified.
How similar studies have performed: Previous research has shown promising results in understanding vascular differences in the brain, suggesting that this approach could yield valuable insights.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARDO-VILLAMIZAR, CARLOS A — JOHNS HOPKINS UNIVERSITY
- Study coordinator: PARDO-VILLAMIZAR, CARLOS A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.