Dietary DHA helps reduce lung inflammation caused by ozone exposure
Dietary DHA mitigates ozone induced pulmonary inflammation
This study is looking at how eating more DHA, a type of omega-3 fatty acid found in fish, might help reduce lung inflammation caused by ozone pollution, and it's for anyone interested in protecting their lung health from air pollution.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10794973 on NIH RePORTER |
What this research studies
This research investigates how dietary docosahexaenoic acid (DHA), an omega-3 fatty acid, can help reduce lung inflammation triggered by ozone pollution. The study focuses on the role of DHA in regulating immune responses in alveolar macrophages, which are key cells involved in lung inflammation. By examining how DHA affects cellular signaling pathways and the production of inflammatory substances, the research aims to identify dietary interventions that could protect against the harmful effects of air pollution on lung health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic pulmonary diseases or those frequently exposed to high levels of ozone pollution.
Not a fit: Patients who do not have any respiratory issues or are not exposed to air pollution may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that help mitigate the health impacts of air pollution on lung function.
How similar studies have performed: Previous research has shown that omega-3 fatty acids can have anti-inflammatory effects, suggesting that this approach may be promising.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Gowdy, Kymberly Mae — Ohio State University
- Study coordinator: Gowdy, Kymberly Mae
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.