Diet Changes for Knee Osteoarthritis Pain
Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain (DIRECTPain)
This project looks at how different diets, like a low-carbohydrate plan, might help adults with knee osteoarthritis find relief from their pain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11095963 on NIH RePORTER |
What this research studies
The project aims to understand if specific diets can help reduce pain and inflammation for people with knee osteoarthritis, a common type of arthritis. We know that low-carbohydrate diets can sometimes lessen inflammation and pain, even without weight loss. This project will provide all meals to participants for six weeks to see how a low-carbohydrate diet compares to a standard healthy diet in reducing knee pain. Researchers will also consider individual differences in metabolism and lifestyle factors to better understand how diet affects pain.
Who could benefit from this research
Good fit: Ideal candidates are adults aged 21 and older who experience chronic pain from knee osteoarthritis.
Not a fit: Patients whose pain is not related to knee osteoarthritis or who are unable to adhere to a specific diet plan may not receive benefit.
Why it matters
Potential benefit: If successful, this work could offer a safe and effective non-drug option for managing chronic knee osteoarthritis pain.
How similar studies have performed: While low-carbohydrate diets have shown promise in reducing inflammation and pain, this project specifically compares different diets in a broad population with knee osteoarthritis, making its findings valuable.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Sorge, Robert — University of Alabama at Birmingham
- Study coordinator: Sorge, Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.