Diagnosing rare and unknown conditions in diverse populations

The Undiagnosed Diseases Network Clinical Site of Miami

NIH-funded research University of Miami School of Medicine · NIH-10978978

This study is looking for people from Hispanic and African American communities who have rare or unknown medical conditions to help find out what might be causing their health issues, so they can get the right diagnosis and care.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine NIH-funded
Lab location1 site (Coral Gables, United States)
Project IDNIH-10978978 on NIH RePORTER

What this research studies

This research focuses on the Undiagnosed Diseases Network (UDN), which aims to diagnose rare and unknown medical conditions, particularly in minority and underserved populations such as Hispanics and African Americans. The UDN Miami Clinical Site is dedicated to increasing participation from these communities by conducting thorough clinical evaluations and utilizing advanced medical facilities for both telehealth and in-person assessments. The initiative seeks to identify novel genetic and non-genetic causes of undiagnosed conditions, with a goal of enrolling at least 40 additional participants annually from underrepresented groups. The study also aims to improve diagnostic outcomes and reduce health disparities.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals from minority and underserved populations, especially those with rare or undiagnosed medical conditions.

Not a fit: Patients who do not have rare or undiagnosed conditions or those outside the targeted minority groups may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnoses and treatment options for patients with rare and undiagnosed conditions, particularly in minority populations.

How similar studies have performed: Other research initiatives have shown success in improving diagnostic rates and outcomes for underserved populations, indicating that this approach has potential for meaningful impact.

Where this research is happening

Coral Gables, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.