Diabetes that starts after a pancreas attack in African American and Hispanic adults
Official title: Mechanisms of diabetes from acute pancreatitis in African Americans and Hispanics
Funded at University of Illinois at Chicago · NIH-11232910 · Data updated 2026-11-12
This project follows Black and Hispanic adults who had acute pancreatitis to learn how and why some go on to develop diabetes afterward.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | September 17, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $477,509 |
| NIH project number | 2U01DK127378-06 |
| Project ID | NIH-11232910 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who recently experienced acute pancreatitis, particularly African American or Hispanic individuals, who can attend clinic visits and provide health information and biospecimens are ideal candidates.
✕Less likely to help
People without a history of acute pancreatitis, children, or anyone unable or unwilling to attend follow-up visits or provide samples are unlikely to benefit from participating.
What this research studies
If you had acute pancreatitis, researchers at the University of Illinois Chicago will invite you to join a long-term group called DREAM where they collect health information, blood and stool samples, and diet details over time. The team includes doctors and scientists from UIC and Northwestern and will combine clinical follow-up with tests of the gut microbiome, metabolism, and other biological markers. They will use modern AI tools to look for patterns that predict who develops diabetes and which factors (like diet or microbes) might play a role. Results will be shared across the consortium to help shape better prevention and monitoring for people like you.
Why it matters
Potential benefit: If successful, this work could help doctors predict who is at higher risk of diabetes after pancreatitis and guide earlier prevention or monitoring, especially for Black and Hispanic patients.
How similar studies have gone: Previous observational studies have linked pancreatitis to later diabetes but the detailed biological mechanisms remain unclear, and combining multi-omics with AI is a newer approach in this area.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Yazici, Cemal — University of Illinois at Chicago
- Study coordinator: Yazici, Cemal
Related research
Other NIH-funded projects on the same topics.
-
Diabetes after acute pancreatitis: understanding and tracking progression
A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.
-
Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Diabetes after acute pancreatitis: a patient-focused network study
A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
-
Epidemiology and causes of diabetes after acute pancreatitis
A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.