Diabetes that appears after acute pancreatitis
Official title: Data Coordinating Center for the Type 1 Diabetes in Acute Pancreatitis Consortium
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11234528 · Data updated 2026-11-12
Following adults who recently had acute pancreatitis to learn how and when diabetes can start afterward.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | September 17, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $1,974,110 |
| NIH project number | 2U01DK127384-06 |
| Project ID | NIH-11234528 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (age 21 and older) who recently experienced an episode of acute pancreatitis and are willing to attend initial and follow-up study visits.
✕Less likely to help
People without a history of acute pancreatitis, children, or those who already had type 1 diabetes before their pancreatitis episode are unlikely to benefit directly from enrolling.
What this research studies
I would join a group of adults who recently had acute pancreatitis and get regular check-ups and tests so researchers can watch who develops diabetes and when. The project aims to enroll up to 1,200 people, with many entering long-term follow-up, and collects blood tests, clinical exams, and immune and genetic measurements. Data from 10 clinical centers and a central coordinating center are pooled to look for early signs, risk factors, and the biological mechanisms behind diabetes after pancreatitis. The team uses this information to identify which subgroups are most at risk and how progression happens over time.
Why it matters
Potential benefit: Could help doctors detect and prevent diabetes that starts after pancreatitis and focus follow-up care on people most likely to develop it.
How similar studies have gone: Smaller observational studies have suggested a link between pancreatitis and later diabetes, but this larger, multi-center prospective cohort is a newer effort to provide stronger evidence.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Chinchilli, Vernon M — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Chinchilli, Vernon M
Related research
Other NIH-funded projects on the same topics.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
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Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
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Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai
This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.
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Understanding how acute pancreatitis may lead to type 1 diabetes
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.