Development of a non-hormonal vaginal product to prevent pregnancy and STIs

Novel pre-coital, non-hormonal multipurpose prevention technology (MPT)

NIH-funded research Population Council · NIH-10772045

This study is testing a new gel called Amphora that helps women prevent both pregnancy and STIs without hormones, making it a great option for those who can't or don't want to use hormonal birth control, like breastfeeding moms.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPopulation Council NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10772045 on NIH RePORTER

What this research studies

This research focuses on creating a multipurpose prevention technology (MPT) that helps women prevent both pregnancy and sexually transmitted infections (STIs) without using hormones. The product, Amphora gel, works by maintaining a low vaginal pH that is hostile to sperm, bacteria, and viruses. It is designed for women who cannot or prefer not to use hormonal contraceptives, including breastfeeding mothers. The research includes ongoing trials to assess its effectiveness against infections like chlamydia and gonorrhea.

Who could benefit from this research

Good fit: Ideal candidates for this research are women, particularly adolescents and breastfeeding mothers, who are seeking non-hormonal contraceptive options.

Not a fit: Patients who are not female or those who are not interested in contraception or STI prevention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide women with a safe and effective non-hormonal option for preventing both pregnancy and STIs.

How similar studies have performed: Other research has shown promise with similar non-hormonal approaches, indicating potential for success in this area.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions communicable disease control agent
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.