Development of a non-hormonal contraceptive intravaginal ring
IND‐enabling development of MM‐008 IVR, an antibody-based nonhormonal contraceptive intravaginal ring
['FUNDING_SBIR_2'] · MUCOMMUNE, LLC · NIH-10706976
This study is testing a new, easy-to-use contraceptive ring that women can insert themselves, which releases a special antibody to help prevent pregnancy without hormones, making it a great option for those who prefer not to use hormonal birth control.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MUCOMMUNE, LLC (nih funded) |
| Locations | 1 site (Morrisville, UNITED STATES) |
| Trial ID | NIH-10706976 on ClinicalTrials.gov |
What this research studies
This research aims to create a new contraceptive method using an intravaginal ring (IVR) that releases a monoclonal antibody to prevent sperm from reaching the egg. The approach focuses on providing a non-hormonal option that is user-controlled and does not require daily dosing or timing with sexual activity. By utilizing a potent anti-sperm antibody, the IVR aims to enhance contraceptive satisfaction and usage among women who are averse to hormonal methods. The research builds on previous animal model validations and leverages recent advancements in antibody production to make this method feasible.
Who could benefit from this research
Good fit: Ideal candidates for this research are women seeking non-hormonal contraceptive methods who may have concerns about hormonal side effects.
Not a fit: Patients who are already satisfied with their current contraceptive methods or those who require hormonal contraception will likely not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide women with a safe, effective, and non-hormonal contraceptive option.
How similar studies have performed: Previous research has validated the concept of using monoclonal antibodies for contraception in animal models, indicating a promising avenue for further development.
Where this research is happening
Morrisville, UNITED STATES
- MUCOMMUNE, LLC — Morrisville, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CONE, RICHARD — MUCOMMUNE, LLC
- Study coordinator: CONE, RICHARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.