Development of a new oral and intranasal malaria vaccine using spirulina.
Phase II STTR development of an intranasal/oral Spirulina-based PfCSP malaria vaccine.
['FUNDING_OTHER'] · LUMEN BIOSCIENCE, INC. · NIH-10910975
This study is testing a new malaria vaccine made from a safe type of blue-green algae that can be taken by mouth or through the nose, making it easier and more comfortable for people to get vaccinated.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LUMEN BIOSCIENCE, INC. (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10910975 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a malaria vaccine that can be administered orally or intranasally, using a safe and nutritious blue-green algae called spirulina. The approach involves genetically engineering spirulina to produce virus-like particles that can stimulate an immune response against malaria. By using this method, the researchers aim to eliminate the pain and logistical challenges associated with traditional injectable vaccines, making vaccination more accessible and compliant for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of malaria infection, particularly those living in endemic regions.
Not a fit: Patients who are not at risk of malaria or those who have already been vaccinated against malaria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a painless and effective malaria vaccine that is easier to distribute and administer.
How similar studies have performed: Previous research has shown success with similar vaccine approaches using virus-like particles, indicating potential for this novel method.
Where this research is happening
SEATTLE, UNITED STATES
- LUMEN BIOSCIENCE, INC. — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KHUONG, NHI — LUMEN BIOSCIENCE, INC.
- Study coordinator: KHUONG, NHI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.