Development of a new contraceptive vaginal film

Core A: Administration

NIH-funded research Boston University Medical Campus · NIH-10923980

This study is testing a new type of birth control called ZB-06, which is a vaginal film that helps prevent pregnancy by using a special antibody to target and stop sperm, giving people a fresh option for contraception.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBoston University Medical Campus NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10923980 on NIH RePORTER

What this research studies

This research focuses on creating a novel contraceptive product called ZB-06, which is a vaginal film that releases an antisperm antibody known as Human Contraception Antibody (HCA). The HCA targets sperm to cause rapid agglutination and immobilization, thereby preventing fertilization. The project is supported by a dedicated Administrative Core that oversees the coordination of various research projects, maintains a clinical database, and ensures that the research progresses effectively. Patients may benefit from this innovative contraceptive method as it aims to provide a new option for birth control.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals or couples looking for new contraceptive options, particularly those who may have difficulty with traditional methods.

Not a fit: Patients who are not seeking contraception or those who have contraindications to using vaginal products may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective contraceptive method for individuals seeking to prevent pregnancy.

How similar studies have performed: While the approach of using antisperm antibodies is innovative, similar methods have shown promise in preliminary studies, indicating potential for success.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.