NIH-funded research Sbir 2 grant

Development of a dual hormone artificial pancreas device

Official title: Advanced Development of Gemini-DHAP

Funded at Sfc Fluidics, LLC · NIH-10892876 · Data updated 2026-11-12

This study is working on a new device called the Gemini-DHAP that automatically gives insulin and glucagon to help people with diabetes manage their blood sugar levels more easily and accurately.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionSfc Fluidics, LLC
NIH-funded
Lab location1 site (Fayetteville, United States)
Project startJuly 25, 2023
Project endJune 30, 2026
Funding year2024
Award (this year)$944,944
NIH project number5R44DK137702-02
Project IDNIH-10892876 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 21 and older with diabetes, particularly those who experience challenges in managing their blood glucose levels.

Less likely to help

Patients who do not have diabetes or those who are not suitable candidates for hormone therapy may not benefit from this research.

What this research studies

This research focuses on creating a new device called the Gemini-DHAP, which is designed to automatically deliver both insulin and glucagon to individuals with diabetes. Using advanced microfluidic technology, the device will respond to real-time glucose readings from a continuous glucose monitor, ensuring precise hormone delivery. The project will involve extensive testing in laboratory and animal models to optimize the device's performance before moving towards clinical trials. Collaborations with medical and regulatory experts will help streamline the path to commercialization.

Why it matters

Potential benefit: If successful, this research could lead to a more effective management system for diabetes, improving blood sugar control and reducing complications for patients.

How similar studies have gone: Previous research on dual hormone delivery systems has shown promise, indicating that this approach could be a significant advancement in diabetes management.

Where this research is happening

  • Sfc Fluidics, LLC
    Fayetteville, United States
    Active

Researchers

  • Principal investigator: Payne, Forrest — Sfc Fluidics, LLC
  • Study coordinator: Payne, Forrest

Related research

Other NIH-funded projects on the same topics.

  • Phenolics-Depleting Chip to improve insulin pumps

    A small, low-power chip is being developed to remove phenolic compounds from insulin before it is delivered by a wearable insulin pump, with the goal of reducing irritation and extending device life.

    NIH research Sfc Fluidics, LLC · Fayetteville, United States · NIH-11401313

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.