Developing vaccines to protect against multiple coronaviruses
PanCorVac (Center for Pan-Coronavirus Vaccine Development)
This study is working on new vaccines that aim to protect against different types of coronaviruses, including the one that causes COVID-19, by training the immune system to recognize parts of the virus that don’t change much, and they’ll first test these vaccines in animals to make sure they’re safe and effective before trying them in people.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10327846 on NIH RePORTER |
What this research studies
This research focuses on creating vaccines that can provide broad protection against various coronaviruses, including SARS-CoV-2. The approach involves shifting the immune response from common virus parts to more conserved regions that are less likely to mutate. The vaccines will be developed using innovative virus-like particles to enhance their effectiveness. Animal models will be used to test the safety and efficacy of these candidate vaccines before they are considered for human trials.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals at high risk for coronavirus infections, such as healthcare workers and those with underlying health conditions.
Not a fit: Patients who are not at risk for coronavirus infections or those who have already been vaccinated against all relevant strains may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to vaccines that protect against multiple strains of coronaviruses, potentially preventing future pandemics.
How similar studies have performed: While there have been successful developments in coronavirus vaccines, this approach to creating a pan-coronavirus vaccine is relatively novel and untested.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Kawaoka, Yoshihiro — University of Wisconsin-Madison
- Study coordinator: Kawaoka, Yoshihiro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.