Developing vaccines to protect against Ebola and related viruses
Advanced Development of Vaccines for Filoviruses
This study is working on a new vaccine that aims to protect people from several serious viruses, like Ebola and Marburg, and it hopes to make it easier to store and distribute, so that one day, patients can have better protection against these infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Auro Vaccines LLC NIH-funded |
| Lab location | 1 site (East Windsor, United States) |
| Project ID | NIH-10867253 on NIH RePORTER |
What this research studies
This research focuses on creating a multivalent vaccine that can protect against multiple filoviruses, including the Ebola virus, Marburg virus, and Lassa Fever. The approach involves formulating a stable vaccine that can be lyophilized for easier storage and distribution. The project will also support the manufacturing process under current good manufacturing practices (cGMP) and prepare for clinical evaluation through the submission of an Investigational New Drug (IND) application. Patients may eventually benefit from a vaccine that provides broader protection against these serious viral infections.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals at high risk for exposure to filoviruses, such as healthcare workers and residents in endemic regions.
Not a fit: Patients who are not at risk for filovirus infections or those who have already been vaccinated against these viruses may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a vaccine that significantly reduces the risk of infection from Ebola and related viruses.
How similar studies have performed: Previous research has shown promise in developing vaccines for filoviruses, indicating that this approach has the potential for success.
Where this research is happening
East Windsor, United States
- Auro Vaccines LLC — East Windsor, United States (Active)
Researchers
- Principal investigator: Eldridge, John — Auro Vaccines LLC
- Study coordinator: Eldridge, John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.