Developing vaccines to protect against dengue and Zika viruses
Strategies for next-generation flavivirus vaccine development
['FUNDING_FELLOWSHIP'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-11221868
This study is working on developing safer and more effective vaccines for dengue and Zika viruses to help protect people from serious health issues caused by these diseases.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (BRONX, UNITED STATES) |
| Trial ID | NIH-11221868 on ClinicalTrials.gov |
What this research studies
This research focuses on creating effective vaccines for dengue and Zika viruses, which are significant health threats in many regions worldwide. The approach aims to generate broadly protective antibodies that can prevent severe complications associated with these viruses, such as hemorrhagic fever and Guillain-Barre syndrome. By understanding how the immune system responds to these viruses, the research seeks to avoid the risks of antibody-dependent enhancement, which can worsen infections. Patients may benefit from safer and more effective vaccination options against these mosquito-borne diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living in or traveling to regions where dengue and Zika viruses are prevalent.
Not a fit: Patients who are not at risk for dengue or Zika virus infections, such as those living in non-endemic areas, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to vaccines that significantly reduce the incidence of severe dengue and Zika virus infections.
How similar studies have performed: Previous research has shown promise in developing vaccines for dengue and Zika viruses, but this approach aims to address specific challenges related to antibody-dependent enhancement, making it a novel effort.
Where this research is happening
BRONX, UNITED STATES
- ALBERT EINSTEIN COLLEGE OF MEDICINE — BRONX, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JUNG, HELEN S — ALBERT EINSTEIN COLLEGE OF MEDICINE
- Study coordinator: JUNG, HELEN S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.