Developing vaccines to protect against dengue and Zika viruses
Official title: Strategies for next-generation flavivirus vaccine development
Funded at Albert Einstein College of Medicine · NIH-11221868 · Data updated 2026-11-12
This study is working on developing safer and more effective vaccines for dengue and Zika viruses to help protect people from serious health issues caused by these diseases.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $53,974 |
| NIH project number | 5F30AI174788-02 |
| Project ID | NIH-11221868 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals living in or traveling to regions where dengue and Zika viruses are prevalent.
✕Less likely to help
Patients who are not at risk for dengue or Zika virus infections, such as those living in non-endemic areas, may not benefit from this research.
What this research studies
This research focuses on creating effective vaccines for dengue and Zika viruses, which are significant health threats in many regions worldwide. The approach aims to generate broadly protective antibodies that can prevent severe complications associated with these viruses, such as hemorrhagic fever and Guillain-Barre syndrome. By understanding how the immune system responds to these viruses, the research seeks to avoid the risks of antibody-dependent enhancement, which can worsen infections. Patients may benefit from safer and more effective vaccination options against these mosquito-borne diseases.
Why it matters
Potential benefit: If successful, this research could lead to vaccines that significantly reduce the incidence of severe dengue and Zika virus infections.
How similar studies have gone: Previous research has shown promise in developing vaccines for dengue and Zika viruses, but this approach aims to address specific challenges related to antibody-dependent enhancement, making it a novel effort.
Where this research is happening
-
Albert Einstein College of Medicine
Bronx, United States Active
Researchers
- Principal investigator: Jung, Helen S — Albert Einstein College of Medicine
- Study coordinator: Jung, Helen S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.