NIH-funded research R01 grant

Developing vaccines to prevent Chlamydia infections

Official title: Bacteriophage virus-like particle vaccines for Chlamydia trachomatis urogenital infection

Funded at University of New Mexico Health Scis Ctr · NIH-10991328 · Data updated 2026-11-12

This study is looking at how to create vaccines that help your immune system fight off Chlamydia, a common sexually transmitted infection, to prevent serious health issues like infertility.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of New Mexico Health Scis Ctr
NIH-funded
Lab location1 site (Albuquerque, United States)
Project startDecember 6, 2022
Project endNovember 30, 2027
Funding year2025
Award (this year)$371,365
NIH project number5R01AI166360-03
Project IDNIH-10991328 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are sexually active individuals, particularly women, who are at risk of Chlamydia infections.

Less likely to help

Patients who are already infected with Chlamydia or those who have had previous infections may not benefit from this preventive vaccine.

What this research studies

This research focuses on creating vaccines that can stimulate the immune system to produce antibodies against Chlamydia trachomatis, a common sexually transmitted infection. The study aims to understand how the immune system responds to this infection and to identify specific proteins that can be targeted by vaccines. By engineering vaccine candidates that elicit strong antibody responses, the research seeks to provide a preventive measure against the serious health complications associated with Chlamydia, such as infertility and pelvic inflammatory disease.

Why it matters

Potential benefit: If successful, this research could lead to an effective vaccine that prevents Chlamydia infections and their associated long-term health issues.

How similar studies have gone: While there have been various approaches to developing vaccines for sexually transmitted infections, this specific method targeting Chlamydia is novel and has not been extensively tested.

Where this research is happening

  • University of New Mexico Health Scis Ctr
    Albuquerque, United States
    Active

Researchers

  • Principal investigator: Frietze, Kathryn M. — University of New Mexico Health Scis Ctr
  • Study coordinator: Frietze, Kathryn M.

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.