Developing vaccines to prepare for future pandemics
Official title: Project 1: Adjuvanted Protein Vaccines for Pandemic Preparedness
Funded at University of California-Irvine · NIH-10863342 · Data updated 2026-11-12
This study is working on new vaccines that can help protect against different viruses that could cause pandemics, and it’s for anyone interested in how we can better prepare for future outbreaks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | August 20, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $7,511,446 |
| NIH project number | 1U19AI181968-01 |
| Project ID | NIH-10863342 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals at risk of exposure to pandemic viruses or those involved in clinical trials for vaccine testing.
✕Less likely to help
Patients who are not at risk for pandemic viruses or those with contraindications to vaccine participation may not benefit from this research.
What this research studies
This research focuses on creating new adjuvanted multivalent recombinant protein vaccines aimed at providing cross-protection against various viruses that pose a pandemic risk. The team will study immune responses and collaborate with other projects to ensure the vaccines are effective. They will conduct tests in animal models, including rodents and non-human primates, and eventually transition to human studies. The project also includes developing a protein microarray for analyzing antibody responses in serum samples.
Why it matters
Potential benefit: If successful, this research could lead to effective vaccines that protect against multiple viruses, enhancing global pandemic preparedness.
How similar studies have gone: Other research has shown promise in developing vaccines using similar approaches, indicating a potential for success in this area.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Liang, Li — University of California-Irvine
- Study coordinator: Liang, Li
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.