Developing vaccines that protect against multiple coronaviruses
Structure-based design of broadly protective coronavirus vaccines
This study is working on new vaccines to help protect people from different types of coronaviruses, including ones that might appear in the future, and it's for anyone interested in staying safe from these viruses.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10425024 on NIH RePORTER |
What this research studies
This research focuses on creating vaccines that can provide broad protection against various coronaviruses, including those that may emerge in the future. The team, consisting of six research groups, will utilize advanced techniques in structure-based vaccine design and immunology to develop two vaccine candidates over the next few years. They aim to produce a pan-sarbecovirus vaccine by the end of Year 2 and a pan-betacoronavirus vaccine by Year 5. The approach includes developing new animal models and tools to evaluate the effectiveness of these vaccines in generating protective immune responses.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals at high risk for coronavirus infections, such as healthcare workers and those with underlying health conditions.
Not a fit: Patients who are not at risk for coronavirus infections or those who have already been vaccinated against specific strains may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to vaccines that offer long-lasting protection against multiple strains of coronaviruses, potentially preventing future pandemics.
How similar studies have performed: Other research efforts have shown promise in developing broadly protective vaccines against viral infections, indicating that this approach has potential for success.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: King, Neil — University of Washington
- Study coordinator: King, Neil
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.