Developing vaccines for pandemic preparedness against specific virus families
Official title: Administrative Core
Funded at University of California-Irvine · NIH-10863337 · Data updated 2026-11-12
This study is working on new vaccines to protect against certain viruses and is looking for ways to make them safe and effective, so we can be ready to fight off these viruses if they start spreading.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | August 20, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $1,775,381 |
| NIH project number | 1U19AI181968-01 |
| Project ID | NIH-10863337 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals at risk for infections caused by Bunyavirus, Paramyxovirus, and Picornavirus, as well as those involved in pandemic response efforts.
✕Less likely to help
Patients with no exposure risk to the targeted viruses or those not involved in pandemic preparedness may not receive direct benefits from this research.
What this research studies
This research focuses on creating a center dedicated to developing vaccines for viruses from the Bunyavirus, Paramyxovirus, and Picornavirus families. The project will evaluate two innovative vaccine platforms: an Adjuvanted Recombinant Protein Vaccine and an mRNA/Lipid Nanoparticle Vaccine. These vaccines will undergo testing for safety, immune response, and effectiveness, ensuring they can be quickly deployed against emerging viral threats. The Administrative Core will coordinate all activities, ensuring efficient operations and collaboration among researchers and partners.
Why it matters
Potential benefit: If successful, this research could lead to the rapid development of effective vaccines for emerging viral infections, enhancing public health preparedness.
How similar studies have gone: Previous research has shown promise in developing rapid response vaccine platforms, indicating potential for success in this novel approach.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Felgner, Philip Louis — University of California-Irvine
- Study coordinator: Felgner, Philip Louis
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.