Developing vaccines and treatments for emerging flaviviruses and alphaviruses
Official title: Flavivirus and Alphavirus ReVAMPP (FLARE)
Funded at Washington University · NIH-10862996 · Data updated 2026-11-12
This study is working on new vaccines and treatments to help protect people from viruses that could cause outbreaks, using the latest technology to quickly adapt to new threats, and it's designed for anyone who wants to stay safe from these illnesses.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | August 12, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $46,715,173 |
| NIH project number | 1U19AI181960-01 |
| Project ID | NIH-10862996 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals at risk of infection from flaviviruses and alphaviruses, such as those living in endemic areas or healthcare workers.
✕Less likely to help
Patients who are not at risk for flavivirus or alphavirus infections may not receive any benefit from this research.
What this research studies
The FLARE Center focuses on creating innovative vaccine platforms and monoclonal antibody treatments to quickly respond to emerging flaviviruses and alphaviruses that could cause pandemics. By utilizing advanced technologies such as protein nanoparticles, virion-based systems, and mRNA vaccines, the research aims to design specific antigens that can be rapidly adapted for new viral threats. The project combines expertise from multiple academic groups and industry partners to ensure the development of effective and safe vaccines and therapies.
Why it matters
Potential benefit: If successful, this research could lead to effective vaccines and treatments that protect against serious viral infections, potentially saving lives during outbreaks.
How similar studies have gone: Previous research has shown success in developing vaccines and treatments for similar viral families, indicating a promising potential for this approach.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Diamond, Michael S — Washington University
- Study coordinator: Diamond, Michael S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.