Developing vaccines and delivery methods for HIV treatment

Vaccine and adjuvant Clinical GMP product development and DNA Technology platform enhancements

['FUNDING_OTHER'] · WISTAR INSTITUTE · NIH-11011264

This study is working on a new type of vaccine to help treat HIV, using special DNA technology, and will test it first in animals before trying it in people, all with the hope of boosting the body's defense against the virus.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorWISTAR INSTITUTE (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11011264 on ClinicalTrials.gov

What this research studies

This research focuses on creating and producing DNA vaccines aimed at treating HIV. The team at Inovio Pharmaceuticals will manufacture these vaccines using advanced techniques and ensure they meet clinical standards. They will also utilize a portable device for delivering the vaccine, which will be tested in animal models before moving to human trials. The goal is to develop effective immunogens that can stimulate the immune response against HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk for HIV or those living with HIV who are seeking new treatment options.

Not a fit: Patients who are not at risk for HIV or those who have already exhausted all treatment options may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective vaccines for preventing and treating HIV infection.

How similar studies have performed: Previous research has shown promise in developing DNA vaccines for various diseases, indicating potential success for this approach in HIV treatment.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.