Developing vaccines and antibodies for peribunyaviruses
Official title: Prototype strategy for vaccines and antibodies to Peribunyaviridae
Funded at Washington University · NIH-10863699 · Data updated 2026-11-12
This study is working on making better vaccines and treatments for illnesses caused by certain viruses, like the Oropouche virus, to help people who might get sick from them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 11, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $6,793,772 |
| NIH project number | 1U19AI181984-01 |
| Project ID | NIH-10863699 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals at risk for infections caused by peribunyaviruses or those with a history of related viral diseases.
✕Less likely to help
Patients who are not at risk for peribunyavirus infections or those with unrelated health conditions may not receive any benefit from this research.
What this research studies
This research focuses on creating effective vaccines and therapeutic antibodies against peribunyaviruses, specifically using the Oropouche virus as a prototype. The team will analyze the structure and function of viral proteins to identify how they interact with the human immune system. By understanding these interactions, the research aims to develop strategies that could lead to stable and effective vaccines and treatments. Patients may benefit from advancements in therapies that target these viruses, which can cause serious diseases.
Why it matters
Potential benefit: If successful, this research could lead to the development of vaccines and treatments that protect against serious viral infections caused by peribunyaviruses.
How similar studies have gone: Other research has shown promise in developing vaccines and antibodies for similar viral families, indicating that this approach has potential for success.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Whelan, Sean Pj — Washington University
- Study coordinator: Whelan, Sean Pj
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.