Developing vaccines and antibodies for arenavirus infections
Vaccines and antibodies for arenaviruses
This study is looking at how to make better vaccines and antibodies to help protect people from arenaviruses, which can cause serious illnesses, and it’s for anyone interested in improving health and safety against these viruses.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10863663 on NIH RePORTER |
What this research studies
This research investigates how to create effective vaccines and antibodies to protect against arenaviruses, which can cause severe diseases like hemorrhagic fever. The project will compare different vaccine technologies and study how the immune system responds to these vaccines using nonhuman primate models. By understanding how to induce strong immune responses, the research aims to develop long-lasting protective measures against various arenaviruses. Additionally, the study will explore the use of engineered antibodies that can provide extended protection for up to a year.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk of exposure to arenaviruses, such as healthcare workers or those living in endemic areas.
Not a fit: Patients who are not at risk of arenavirus infections or those with existing immunity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective vaccines and treatments that significantly reduce the risk of severe arenavirus infections in humans.
How similar studies have performed: Previous research has shown promise in developing vaccines for other viral infections, suggesting that similar approaches may be effective for arenaviruses.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Carnahan, Robert H — Vanderbilt University Medical Center
- Study coordinator: Carnahan, Robert H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.