Developing treatments for injuries caused by radiation exposure
Official title: NON-CLINICAL STUDIES IN SUPPORT OF IND/NDA/BLA SUBMISSIONS
Funded at Sri International · NIH-11194213 · Data updated 2026-11-12
This study is looking at new ways to help people who have been hurt by radiation, using animal tests to see how well these treatments work and to learn more about measuring radiation exposure.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sri International NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project start | September 1, 2022 |
| Project end | September 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $2,133,733 |
| NIH project number | 75N93020D00011-P00002-759302200001-1 |
| Project ID | NIH-11194213 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have been exposed to radiation and are at risk of radiation-related injuries.
✕Less likely to help
Patients who have not been exposed to radiation or do not have radiation-related injuries may not benefit from this research.
What this research studies
This research focuses on creating and testing medical countermeasures to treat injuries resulting from radiation exposure. Using animal models, the team will evaluate the efficacy of these treatments and gather samples for biodosimetry studies, which help measure radiation exposure levels. The approach aims to enhance our understanding of how to effectively mitigate the effects of radiation injuries, potentially leading to improved medical interventions.
Why it matters
Potential benefit: If successful, this research could lead to effective treatments for individuals suffering from radiation injuries.
How similar studies have gone: Previous research has shown promise in developing medical countermeasures for radiation injuries, indicating that this approach has potential for success.
Where this research is happening
-
Sri International
Menlo Park, United States Active
Researchers
- Principal investigator: Chang, Polly Yee — Sri International
- Study coordinator: Chang, Polly Yee
Related research
Other NIH-funded projects on the same topics.
-
ABCD-USA Consortium: A large, long-term study tracking brain development in youth
A large, long-term study at multiple sites is following thousands of children and teens to understand how their brains grow and relate to health, behavior, and environment.
-
BioCyc, MetaCyc, and EcoCyc knowledge bases expansion with AI assistance
Aims to speed up and improve the BioCyc family of knowledge bases that map genomes and metabolic pathways, using AI to accelerate data curation for researchers who study microbes and metabolism.
-
Tracking HIV, alcohol use, and brain aging with MRI
Aging people living with HIV who also have alcohol use disorder are being studied to understand how brain changes relate to balance, movement, and thinking over time using MRI.
-
NCANDA-SRI: Studying how adolescent drinking affects brain development and adulthood
A long-term study at SRI International follows teens who started drinking to see how it may change brain development and risk for alcohol use disorders as they grow into adults.
-
Brain changes behind thinking and movement problems in older people with HIV and Parkinson's
This project looks at brain changes that may explain why older people living with HIV sometimes have thinking and movement problems similar to Parkinson's.
-
ABCD brain and child development project at SRI
Following children who were 9–10 years old to learn how their brains, health, and behavior change from childhood into young adulthood.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.