NIH-funded research NIH-funded research

Developing treatments for injuries caused by radiation exposure

Official title: DECORPORATION MCM PHASE 1 CLINICAL SAFETY STUDY

Funded at Sri International · NIH-11041810 · Data updated 2026-11-12

This study is looking at new ways to help people who have been hurt by radiation, using tests on animals to see if these treatments are safe and work well, with the hope that it will lead to better options for patients in the future.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSri International
NIH-funded
Lab location1 site (Menlo Park, United States)
Project startSeptember 1, 2021
Project endAugust 31, 2025
Funding year2024
Award (this year)$2,898,062
NIH project number75N93020D00011-P00005-759302100001-1
Project IDNIH-11041810 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have been exposed to radiation or are at risk of radiation exposure.

Less likely to help

Patients who have not been exposed to radiation or do not have conditions related to radiation injuries may not benefit from this research.

What this research studies

This research focuses on creating and testing medical countermeasures to treat injuries resulting from radiation exposure. Using animal models, the study aims to evaluate the safety and effectiveness of these treatments. The research also involves collecting samples for biodosimetry studies, which help assess radiation exposure levels. Patients may benefit from advancements in treatment options for radiation injuries as a result of this work.

Why it matters

Potential benefit: If successful, this research could lead to effective treatments for patients suffering from radiation injuries.

How similar studies have gone: While there have been studies on radiation injuries, the specific approach of developing medical countermeasures in this context is relatively novel.

Where this research is happening

  • Sri International
    Menlo Park, United States
    Active

Researchers

  • Principal investigator: Chang, Polly Yee — Sri International
  • Study coordinator: Chang, Polly Yee

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.