Developing treatments for cancers caused by RAS gene mutations
Official title: RAS Program at FNL
Funded at Leidos Biomedical Research, INC. · NIH-11219759 · Data updated 2026-11-12
This study is working on new treatments for certain types of cancer caused by changes in the HRAS gene, and it brings together top scientists and technology to help create better options for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Leidos Biomedical Research, INC. NIH-funded |
| Lab location | 1 site (Frederick, United States) |
| Project start | September 28, 2024 |
| Project end | August 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $12,689,844 |
| NIH project number | 75N91019D00024-0-759102400011-12 |
| Project ID | NIH-11219759 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with cancers associated with mutations in the RAS gene.
✕Less likely to help
Patients with cancers not related to RAS gene mutations may not benefit from this research.
What this research studies
This research focuses on creating targeted therapies for cancers that are driven by abnormal signaling from the RAS gene, particularly those caused by mutations in the HRAS gene. The program operates through a collaborative model, bringing together scientific leaders and advanced technologies at the Frederick National Laboratory for Cancer Research. Patients may benefit from innovative treatment strategies that emerge from this research, which aims to address the underlying genetic causes of their cancers.
Why it matters
Potential benefit: If successful, this research could lead to new, effective treatments for patients with cancers linked to RAS gene mutations.
How similar studies have gone: Previous research has shown promise in targeting RAS-driven cancers, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
-
Leidos Biomedical Research, INC.
Frederick, United States Active
Researchers
- Principal investigator: Briscoe, Lynn — Leidos Biomedical Research, INC.
- Study coordinator: Briscoe, Lynn
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.