Developing treatments and biomarkers for preventing acquired epilepsy
Translational Platform for Epilepsy Therapy and Biomarker Discovery
This study is looking for ways to help people who might develop epilepsy after a brain injury by finding early signs of risk and testing a new treatment that removes harmful iron from the brain, so those at risk can get help sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11056718 on NIH RePORTER |
What this research studies
This research focuses on creating effective treatments to prevent acquired epilepsies, particularly post-traumatic epilepsy, by identifying early biomarkers that indicate who is at risk. The team will utilize a preclinical model to test a new candidate treatment that aims to remove harmful iron from the brain. By following rigorous scientific standards and collaborating with multiple international research centers, the study seeks to enhance the understanding of epilepsy and improve treatment strategies. Patients who are identified as at risk could potentially benefit from early intervention based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced traumatic brain injuries or other conditions that may increase their risk of developing epilepsy.
Not a fit: Patients who do not have a history of traumatic brain injury or other risk factors for acquired epilepsy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective treatments that prevent the onset of epilepsy in at-risk individuals.
How similar studies have performed: Previous research has shown promise in identifying biomarkers and developing treatments for epilepsy, but this specific approach is innovative and aims to fill a critical gap in prevention strategies.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Galanopoulou, Aristea S — Albert Einstein College of Medicine
- Study coordinator: Galanopoulou, Aristea S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.