Developing tools to study and manipulate biological processes in cancer cells
Official title: Core 3: Chemical Biology & Materials Tools (CBMT)
Funded at University of Pennsylvania · NIH-11085260 · Data updated 2026-11-12
This study is working on new tools that help scientists better understand cancer by using light to control how they study cells, which could lead to better treatments for patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | May 8, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $142,409 |
| NIH project number | 5P01CA265794-03 |
| Project ID | NIH-11085260 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals diagnosed with cancer who may be eligible for new treatment strategies arising from this innovative research.
✕Less likely to help
Patients with non-cancerous conditions or those not involved in ongoing cancer research may not receive direct benefits from this research.
What this research studies
This research focuses on creating advanced chemical biology tools that can probe, manipulate, and visualize biological systems, particularly in the context of cancer. By developing optically triggered variants of these tools, researchers aim to gain deeper insights into key biological pathways and processes with unprecedented control over timing and location. The project will customize these tools to meet the specific needs of various cancer research projects, enhancing the understanding of tumor biology and immune responses. Patients may benefit from the innovative approaches that could lead to new cancer treatments.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel therapies that enhance the anti-tumor immune response and improve cancer treatment outcomes.
How similar studies have gone: Previous research has shown success in using chemical biology tools to manipulate biological processes, indicating a promising avenue for further exploration in cancer treatment.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Chenoweth, David Michael — University of Pennsylvania
- Study coordinator: Chenoweth, David Michael
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.