Developing tools to predict side effects from radiation treatment
Official title: Development of Radiation/Nuclear Medical Countermeasures (MCMs) and Biodosimetry Devices
Funded at Chromologic, LLC · NIH-11105742 · Data updated 2026-11-12
This study is looking to develop a test that can help predict if patients receiving radiation therapy for cancers like sarcoma and head and neck cancer might experience side effects like low white blood cell counts or lung issues, so doctors can better manage their care and improve their treatment experience.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Chromologic, LLC NIH-funded |
| Lab location | 1 site (Monrovia, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $2,280,705 |
| NIH project number | 75N93023C00016-P00003-9999-1 |
| Project ID | NIH-11105742 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing radiation treatment for sarcoma or head and neck cancer.
✕Less likely to help
Patients not receiving radiation therapy or those with cancers not included in the study may not benefit from this research.
What this research studies
This research focuses on creating and validating a panel of microRNAs that can predict adverse effects such as neutropenia and fibrosis in patients undergoing radiation therapy for cancers like sarcoma and head and neck cancer. The study involves collaboration with several prominent cancer centers to ensure comprehensive evaluation and aims to secure FDA approval for these predictive tools. By identifying patients at risk for these complications, the research seeks to improve patient management and treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to better prediction and management of side effects from radiation therapy, enhancing the quality of care for cancer patients.
How similar studies have gone: Previous research has shown promise in using microRNA panels for predicting treatment-related side effects, indicating a potential for success in this approach.
Where this research is happening
-
Chromologic, LLC
Monrovia, United States Active
Researchers
- Principal investigator: Nguyen, Theresa — Chromologic, LLC
- Study coordinator: Nguyen, Theresa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.