Developing tools to identify and track brain health in patients with vascular contributions to cognitive impairment and dementia.
The University of Kentucky MarkVCID Biomarker Validation Cohort: Development of a Toolbox to Advance VCID Interventional Studies
This study is looking for ways to better understand and track brain health in people with small vessel disease, especially those at risk for heart problems, by using tests like MRI scans and blood tests, so that we can improve how we diagnose and treat memory and thinking issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10611830 on NIH RePORTER |
What this research studies
This research focuses on identifying and validating biomarkers related to cerebral small vessel disease (cSVD) to improve diagnosis and tracking of cognitive impairment and dementia. Participants will undergo various assessments, including MRI scans, blood tests, and neuropsychological evaluations, to help create a comprehensive toolbox for future clinical trials. The study aims to enhance our understanding of how vascular issues contribute to cognitive decline, particularly in individuals with cardiovascular risk factors. By participating, patients will contribute to a significant effort to improve diagnostic and treatment strategies for cognitive impairment.
Who could benefit from this research
Good fit: Ideal candidates include individuals with cardiovascular risk factors, subjective memory complaints, or mild cognitive impairment.
Not a fit: Patients without cardiovascular risk factors or significant cognitive concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for patients experiencing cognitive decline due to vascular issues.
How similar studies have performed: Previous research has shown promise in using biomarkers for cognitive impairment, making this approach both relevant and potentially impactful.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Jicha, Gregory a — University of Kentucky
- Study coordinator: Jicha, Gregory a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.