Developing tools to detect immune responses to COVID-19
COVID Supplement - NIH Tetramer Core Facility
This study is working on creating special tools to help scientists better understand how our immune system fights COVID-19, focusing on specific types of immune cells, and it's aimed at helping researchers who are studying the virus and developing vaccines.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10489924 on NIH RePORTER |
What this research studies
This research focuses on creating and distributing high-quality reagents that help detect specific T cell populations involved in the immune response to COVID-19. The NIH Tetramer Core Facility is working on producing MHC class I and class II tetramers that can isolate and characterize CD4 and CD8 T cells specific to SARS-CoV-2. Additionally, they are developing tetramers for the SARS-CoV-2 Spike protein to identify and study B cells. These reagents will support ongoing research into how the immune system responds to COVID-19 and potential vaccines.
Who could benefit from this research
Good fit: Patients who have been infected with SARS-CoV-2 or are participating in COVID-19 vaccine trials would be ideal candidates for this research.
Not a fit: Patients who have not been exposed to SARS-CoV-2 or are not involved in related research may not benefit from this work.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of immune responses to COVID-19, leading to better diagnostics and treatments.
How similar studies have performed: Other research has successfully utilized similar tetramer technologies to study immune responses, indicating a promising approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Altman, John — Emory University
- Study coordinator: Altman, John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.