Developing tools to better predict colorectal cancer risk and progression

Building Data Science Tools for Genetic Models of Colorectal Cancer Progression and Risk

NIH-funded research Durham VA Medical Center · NIH-10950354

This study is looking at how your genes can help predict your risk of colorectal cancer, so that doctors can give you personalized screening recommendations based on your unique genetic makeup, making it easier to catch any issues early.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDurham VA Medical Center NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10950354 on NIH RePORTER

What this research studies

This research focuses on improving the prediction of colorectal cancer (CRC) risk by utilizing genetic and genomic data. It aims to create integrated data resources that account for individual variability in CRC risk factors, which can help tailor screening recommendations based on a person's specific genetic profile. By analyzing longitudinal data on CRC precursors and their progression, the research seeks to develop personalized risk models that can enhance the effectiveness of CRC screening and surveillance. This approach could lead to more timely and appropriate interventions for those at higher risk.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a family history of colorectal cancer or those identified as high-risk based on genetic factors.

Not a fit: Patients with no genetic predisposition to colorectal cancer or those who are not at risk may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate CRC risk assessments and improved screening strategies, ultimately reducing CRC incidence and mortality.

How similar studies have performed: Previous research has shown promise in using genetic data to improve cancer risk prediction, indicating that this approach has potential for success.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.