Developing tools for a new cancer treatment using electrical pulses
Academic-Industrial Partnership to Develop Clinical Tools for Algorithmic Irreversible Electroporation of Inoperable Tumors
This study is exploring a new way to treat hard-to-remove liver and pancreatic tumors in dogs using a technique that sends quick electrical pulses to help kill the cancer cells, and we're excited to see how it works in our furry friends before it can be used in clinics.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-10916238 on NIH RePORTER |
What this research studies
This research focuses on a novel treatment for inoperable liver and pancreatic tumors using a technique called Algorithmically Controlled Electroporation (ACE). By applying brief electrical pulses, this method aims to induce cell death in tumors that are difficult to remove surgically. The project involves creating clinical instruments and disposable applicators for this treatment, which will be tested in animal models before being applied to canine patients with liver cancer. The goal is to transition this innovative technology from laboratory validation to practical use in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with inoperable liver or pancreatic cancer who are not suitable for surgical resection.
Not a fit: Patients with operable tumors or those who do not have liver or pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, minimally invasive treatment option for patients with inoperable liver and pancreatic tumors.
How similar studies have performed: Previous studies have shown promising results with similar electroporation techniques, indicating potential for success in this novel application.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Sano, Michael Benjamin — North Carolina State University Raleigh
- Study coordinator: Sano, Michael Benjamin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.