Developing tiny particles to deliver medicine for muscle conditions
A novel framework for nanomedicine development
This project aims to create new ways to deliver medicines using very small particles, called nanoparticles, to help people with muscle diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma NIH-funded |
| Lab location | 1 site (Norman, United States) |
| Project ID | NIH-11144453 on NIH RePORTER |
What this research studies
Researchers are working on a new approach to create tiny particles that can safely and effectively carry drugs and genetic material directly to muscle cells. The goal is to overcome challenges in getting these nanoparticles to the right places in the body, ensuring they work well and are safe. This involves designing new nanoparticles, using advanced imaging techniques to see how they move, and carefully measuring their safety and effectiveness. Ultimately, this work seeks to make a big step forward in treating skeletal muscle disorders.
Who could benefit from this research
Good fit: This foundational research is not yet recruiting patients, but future clinical applications would target individuals living with skeletal muscle disorders.
Not a fit: Patients without skeletal muscle disorders would not directly benefit from the specific therapeutic applications developed through this research.
Why it matters
Potential benefit: If successful, this work could lead to safer and more effective treatments for various muscle diseases by improving how medicines reach the affected cells.
How similar studies have performed: While nanomedicine is an active field, this project proposes a novel framework and aims for a major breakthrough in non-viral delivery to muscle tissue.
Where this research is happening
Norman, United States
- University of Oklahoma — Norman, United States (Active)
Researchers
- Principal investigator: Wilhelm, Stefan — University of Oklahoma
- Study coordinator: Wilhelm, Stefan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.