Developing tiny particles to deliver medicine for muscle conditions
Official title: A novel framework for nanomedicine development
Funded at University of Oklahoma · NIH-11144453 · Data updated 2026-11-12
This project aims to create new ways to deliver medicines using very small particles, called nanoparticles, to help people with muscle diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma NIH-funded |
| Lab location | 1 site (Norman, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $373,297 |
| NIH project number | 5R35GM150758-03 |
| Project ID | NIH-11144453 on NIH RePORTER |
Who could benefit from this research
✓Could help
This foundational research is not yet recruiting patients, but future clinical applications would target individuals living with skeletal muscle disorders.
✕Less likely to help
Patients without skeletal muscle disorders would not directly benefit from the specific therapeutic applications developed through this research.
What this research studies
Researchers are working on a new approach to create tiny particles that can safely and effectively carry drugs and genetic material directly to muscle cells. The goal is to overcome challenges in getting these nanoparticles to the right places in the body, ensuring they work well and are safe. This involves designing new nanoparticles, using advanced imaging techniques to see how they move, and carefully measuring their safety and effectiveness. Ultimately, this work seeks to make a big step forward in treating skeletal muscle disorders.
Why it matters
Potential benefit: If successful, this work could lead to safer and more effective treatments for various muscle diseases by improving how medicines reach the affected cells.
How similar studies have gone: While nanomedicine is an active field, this project proposes a novel framework and aims for a major breakthrough in non-viral delivery to muscle tissue.
Where this research is happening
-
University of Oklahoma
Norman, United States Active
Researchers
- Principal investigator: Wilhelm, Stefan — University of Oklahoma
- Study coordinator: Wilhelm, Stefan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.