Developing tests to improve HIV treatment for patients with drug resistance
Assay Development and Validation for Precision Antiretroviral Therapy to Combat Drug Resistance
This study is working on new tests to help doctors understand why some people with HIV don’t respond to regular treatments, so they can create better, personalized options to help manage the virus and improve health for those patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project ID | NIH-10882256 on NIH RePORTER |
What this research studies
This research focuses on creating and validating new assays to better understand and combat drug resistance in HIV-positive patients. By utilizing advanced techniques, including a novel infectivity assay that visualizes infected cells, the project aims to provide more accurate predictions of treatment outcomes for individuals who struggle with standard antiretroviral therapies. The goal is to develop personalized treatment options that can effectively manage viral loads in patients who do not respond to existing therapies. This approach seeks to enhance patient care and improve overall health outcomes for those affected by HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-positive individuals who have not achieved viral suppression despite receiving combination antiretroviral therapy.
Not a fit: Patients who are newly diagnosed with HIV and have not yet started treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with HIV who are experiencing drug resistance.
How similar studies have performed: Previous research has shown promise in developing assays for HIV drug resistance, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Fort Collins, United States
- Colorado State University — Fort Collins, United States (Active)
Researchers
- Principal investigator: Chen, Chaoping — Colorado State University
- Study coordinator: Chen, Chaoping
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.