Developing tests to identify early-stage lung cancer and predict recurrence risk
Official title: Biomarker Reference Lab
Funded at New York University School of Medicine · NIH-11081764 · Data updated 2026-11-12
This study is working on new lab tests that can help find lung cancer early and check if it might come back after surgery, using blood and airway samples to look for specific markers, so if you have lung cancer, this research could lead to better ways to monitor your health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 4, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $339,874 |
| NIH project number | 5U2CCA271890-03 |
| Project ID | NIH-11081764 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with early-stage non-small cell lung cancer (NSCLC) who are undergoing surgical treatment.
✕Less likely to help
Patients with advanced-stage lung cancer or those not undergoing surgery may not benefit from this research.
What this research studies
This research focuses on creating advanced laboratory tests that can detect early-stage lung cancer and assess the likelihood of cancer returning after surgery. By analyzing blood and airway samples, the study aims to identify specific microbial and genomic markers associated with lung cancer. The research employs innovative techniques such as next-generation sequencing and metabolite profiling to develop reliable diagnostic tools. Patients' samples will be matched with those used in earlier discovery phases to ensure accurate validation of these tests.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of lung cancer and better management of recurrence risk for patients.
How similar studies have gone: Previous research has shown promise in using genomic and microbial markers for cancer detection, indicating a potential for success in this novel approach.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Segal, Leopoldo Nicolas — New York University School of Medicine
- Study coordinator: Segal, Leopoldo Nicolas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.