Developing tests to identify cancer risk in patients with Barrett's esophagus and colorectal conditions
Biomarker Developmental Unit
This study is working on new tests that look for specific genetic changes to help find esophageal and colorectal cancers earlier in people who might be at higher risk, so they can get the right follow-up care and improve their chances of staying healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10884391 on NIH RePORTER |
What this research studies
This research focuses on improving cancer screening methods for esophageal adenocarcinoma and colorectal cancer by developing new tests that detect specific genetic changes in patients. The approach involves using methylated DNA biomarker assays to identify individuals at high risk for these cancers, allowing for more tailored and effective follow-up procedures. By validating these tests in clinical settings, the research aims to enhance early detection and risk prediction, ultimately preventing cancer progression and improving patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with Barrett's esophagus or those at risk for colorectal cancer due to adenomas.
Not a fit: Patients without Barrett's esophagus or colorectal adenomas may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate cancer screenings and prevent deaths from esophageal adenocarcinoma and colorectal cancer.
How similar studies have performed: Previous research has shown promise in using genetic and epigenetic markers for cancer detection, indicating a potential for success in this novel approach.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Yeung, Cecilia C — Fred Hutchinson Cancer Center
- Study coordinator: Yeung, Cecilia C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.