Developing tests to detect ovarian cancer using uterine fluid samples
Biomarker Developmental Laboratory (BDL)
['FUNDING_OTHER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10674909
This study is working on new tests that use samples from the uterus to help find ovarian cancer earlier and more accurately, using advanced technology to look at genes and proteins in the samples.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10674909 on ClinicalTrials.gov |
What this research studies
This research focuses on creating and validating advanced genomic and proteomic tests to identify ovarian cancer through samples collected from uterine lavage. By analyzing the genetic material and proteins in these samples, researchers aim to enhance the sensitivity of cancer detection. The study employs machine learning techniques to improve the accuracy of the results, ensuring that the tests can differentiate between cancerous and non-cancerous cells effectively. The ultimate goal is to develop a reliable panel of biomarkers that can be used in clinical settings for early detection of ovarian cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who are at risk for ovarian cancer or those presenting with symptoms suggestive of the disease.
Not a fit: Patients who have already been diagnosed with advanced ovarian cancer or those without any risk factors for ovarian cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of ovarian cancer, improving treatment outcomes for patients.
How similar studies have performed: Previous research has shown promise in using similar genomic and proteomic approaches for cancer detection, indicating potential for success in this novel application.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SKATES, STEVEN J — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: SKATES, STEVEN J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.